The association between human papillomavirus and bladder cancer: Evidence from meta-analysis and two-sample mendelian randomization.

ABSTRACT:

Introduction

Bladder cancer (BCa) is the 10th most common type of cancer worldwide, and human papillomavirus (HPV) is the most common sexually transmitted infection. However, the relationship between HPV infection and the risk of BCa is still controversial and inconclusive.

Methods

This systematic review and meta-analysis were conducted following the PRISMA 2020 reporting guideline. This study searched four bibliographic databases with no language limitation. The databases included PubMed (Medline), EMBASE, Cochrane Library, and Web of Science. Studies evaluating the interaction between HPV infection and the risk of BCa from inception through May 21, 2022, were identified and used in this study. This study estimated the overall and type-specific HPV prevalence and 95% confid

SUBMITTER: Sun JX 

PROVIDER: S-EPMC10092419 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature