Clinical and laboratory features of patients diagnosed with alpha-gal syndrome-2010-2019.

ABSTRACT:

Background

Alpha-gal syndrome (AGS) is an IgE-mediated allergy to galactose-alpha-1,3-galactose. Clinical presentation ranges from hives to anaphylaxis; episodes typically occur 2-6 h after exposure to alpha-gal-containing products. In the United States, lone star tick bites are associated with the development of AGS. To characterize features of AGS, we evaluated a cohort of patients presenting for care at the University of North Carolina, focusing on symptoms, severity, and identifying features unique to specific alpha-gal-containing product exposures.

Methods

We performed a chart review and descriptive analysis of 100 randomly selected patients with AGS during 2010-2019.

Results

Median age at onset was 53 years, 56% were female, 95% reported White race, 86% reported

SUBMITTER: Binder AM 

PROVIDER: S-EPMC10092820 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature