Biomarkers of potential harm in people switching from smoking tobacco to exclusive e-cigarette use, dual use or abstinence: secondary analysis of Cochrane systematic review of trials of e-cigarettes for smoking cessation.

ABSTRACT:

Aims

This study aims to compare biomarkers of potential harm between people switching from smoking combustible cigarettes (CC) completely to electronic cigarettes (EC), continuing to smoke CC, using both EC and CC (dual users) and using neither (abstainers), based on behaviour during EC intervention studies.

Design

Secondary analysis following systematic review, incorporating inverse variance random-effects meta-analysis and effect direction plots.

Setting

This study was conducted in Greece, Italy, Poland, the United Kingdom and the United States.

Participants

A total of 1299 adults smoking CC (nine studies) and provided EC.

Measurements

Measurements were conducted using carbon monoxide (CO) and 26 other biomarkers.

Findings

In pooled analyses, ex

SUBMITTER: Hartmann-Boyce J 

PROVIDER: S-EPMC10092879 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature