Impact of comorbidities on atrial fibrillation and sudden cardiac death in hypertrophic cardiomyopathy.

ABSTRACT:

Background

The impact of comorbid disease states on the development of atrial and ventricular arrhythmias in patients with hypertrophic cardiomyopathy (HCM) remains unresolved.

Objective

Evaluate the association of comorbidities linked to arrhythmias in other cardiovascular diseases (e.g., obesity, systemic hypertension, diabetes, obstructive sleep apnea, renal disorders, tobacco, and alcohol use) to atrial fibrillation (AF) and sudden cardiac death (SCD) events in a large cohort of HCM patients.

Methods

A total  of 2269 patients, 54 ± 15 years of age, 1392 males, were evaluated at the Tufts HCM Institute between 2004 and 2018 and followed for an average of 4 ± 3 years for new-onset clinical AF and SCD events (appropriate defibrillation for ventricular tachyarrhythmia

SUBMITTER: Sridharan A 

PROVIDER: S-EPMC10092906 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature