Liquid Biopsy in the Management of Breast Cancer Patients: Where Are We Now and Where Are We Going.

ABSTRACT: Liquid biopsy (LB) is an emerging diagnostic tool that analyzes biomarkers in the blood (and possibly in other body fluids) to provide information about tumor genetics and response to therapy. This review article provides an overview of LB applications in human cancer with a focus on breast cancer patients. LB methods include circulating tumor cells and cell-free tumor products, such as circulating tumor DNA. LB has shown potential in detecting cancer at an early stage, monitoring tumor progression and recurrence, and predicting patient response to therapy. Several studies have demonstrated its clinical utility in breast cancer patients. However, there are limitations to LB, including the lack of standardized assays and the need for further validation. Future potential applications of LB i

SUBMITTER: Mazzitelli C 

PROVIDER: S-EPMC10092978 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature