Consensus for Flow Cytometry Clinical Report on Multiple Myeloma: A Multicenter Harmonization Process Merging Laboratory Experience and Clinical Needs

ABSTRACT:

Simple Summary

We report an Italian multicentre study with the aim to reach a consensus based on the essential data to be included in the flow cytometry clinical report of patients with MM at diagnosis and after treatment. From the pre-analytical phase, through sample processing, data acquisition, analysis and evaluation of the potential limitations and pitfalls of the entire process, the study reaches a final conclusion shared by laboratories and clinicians according to the most up-to-date principles and recommendations.

Abstract

Flow cytometry is a highly sensitive and specific approach for discriminating between normal and clonal plasma cells in multiple myeloma. Uniform response criteria after treatment have been established by the International Myeloma Working Group

SUBMITTER: Cordone I 

PROVIDER: S-EPMC10093543 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature