New gene markers for classification and quantification of Faecalibacterium spp. in the human gut.

ABSTRACT: Faecalibacterium prausnitzii is a promising biomarker of a healthy human microbiota. However, previous studies reported the heterogeneity of this species and found the presence of several distinct groups at the species level among F. prausnitzii strains. Our recent study revealed that methods previously developed for quantification of F. prausnitzii were not specific to the species level because of the heterogeneity within the F. prausnitzii species and the application of 16S rRNA gene, which is an invalid genetic marker for the species. Therefore, previously available data failed to provide information on different groups, which limits our understanding of the importance of this organism for host health. Here, we propose an alternative gene marker for quantification of F. prausnitzii-rela

SUBMITTER: Tanno H 

PROVIDER: S-EPMC10093996 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature