Assessing population substructure in the Lebanese population: A population study using data on 23 autosomal short tandem repeats.

ABSTRACT:

Background

Understanding the genetic substructure of a population is essential for proper forensic genetic analysis. The Lebanese population has a high rate of endogamous and consanguineous marriages and is segregated based on religious belongings. However, no genetic population studies have been performed up to date to estimate the degree of genetic substructure and inbreeding coefficients.

Methods

The present study analyzed a compendium of 23 autosomal STRs typed in 1400 individuals belonging to the seven major Lebanese religious subcommunities. Inbreeding coefficients such as F statistics were estimated.

Results

Results showed a Fst (theta) value of 0.002, indicating a low genetic subdivision within the Lebanese population.

Conclusion

This study aimed at ass

SUBMITTER: El Andari A 

PROVIDER: S-EPMC10094076 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature