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Mesoporous Silica Nanoparticles as a Potential Nanoplatform: Therapeutic Applications and Considerations.


ABSTRACT: With advances in nanotechnology, nanoparticles have come to be regarded as carriers of therapeutic agents and have been widely studied to overcome various diseases in the biomedical field. Among these particles, mesoporous silica nanoparticles (MSNs) have been investigated as potential nanocarriers to deliver drug molecules to various target sites in the body. This review introduces the physicochemical properties of MSNs and synthesis procedures of MSN-based nanoplatforms. Moreover, we focus on updating biomedical applications of MSNs as a carrier of therapeutic or diagnostic cargo and review clinical trials using silica-nanoparticle-based systems. Herein, on the one hand, we pay attention to the pharmaceutical advantages of MSNs, including nanometer particle size, high surface area, and p

SUBMITTER: Djayanti K 

PROVIDER: S-EPMC10094416 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature