Molecular Investigation of the Fatal Bloodstream Candida orthopsilosis Infection Case following Gastrectomy.

ABSTRACT: Candida orthopsilosis represents a closely related cryptic genospecies of Candida parapsilosis complex-misidentified in routine diagnostic assays. This is emerging in settings where central venous catheters, invasive medical interventions, and echinocandin treatments are most likely to be used. A 59-year-old, non-neutropenic male patient, was admitted to an intensive care unit (ICU) due to respiratory distress syndrome, following a partial gastrectomy. As a result of duodenal stump leakage, re-laparotomy was required, abdominal drains were provided and central line catheters were exchanged. Multiple isolates of Candida orthopsilosis drawn from consecutive blood cultures were identified, despite ongoing echinocandin therapy and confirmed in vitro echinocandins susceptib

SUBMITTER: Mnichowska-Polanowska M 

PROVIDER: S-EPMC10094972 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature