Endovascular Treatment for Acute Basilar Artery Occlusion: A Fragility Index Meta-Analysis.

ABSTRACT:

Introduction

High-quality evidence regarding the use of endovascular treatment (EVT) in patients with acute basilar artery occlusion (BAO) has been provided by recently completed randomized controlled clinical trials (RCTs).

Methods

We conducted a systematic review and meta-analysis including all available RCTs that investigated efficacy and safety of EVT in addition to best medical treatment (BMT) versus BMT alone for BAO. The random-effects model was used, while the fragility index (FI) was calculated for dichotomous outcomes of interest.

Results

Four RCTs were included comprising a total of 988 patients with acute BAO (mean age: 65.6 years, 70% men, median NIHSS: 24, 39% pretreatment with intravenous thrombolysis). EVT was related to higher likelihood of good funct

SUBMITTER: Palaiodimou L 

PROVIDER: S-EPMC10094975 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature