Moisturizing and Antioxidant Effects of Artemisia argyi Essence Liquid in HaCaT Keratinocytes.

ABSTRACT: Artemisia argyi essence liquid (AL) is an aqueous solution extracted from A. argyi using CO₂ supercritical fluid extraction. There have been few investigations on the aqueous solution of A. argyi extracted via CO₂ supercritical fluid extraction. This study aimed to explore the moisturizing and antioxidant effects of AL and to clarify the potential mechanism underlying those effects. Expression levels of skin moisture-related components and the H₂O₂-induced oxidative stress responses in human keratinocyte cells were measured via quantitative RT-qPCR, Western blot, and immunofluorescence. Our results showed that AL enhanced the expression of AQP3 and HAS2 by activating the EGFR-mediated STAT3 and MAPK signaling pathways. In add

SUBMITTER: Wang Z 

PROVIDER: S-EPMC10095007 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature