Estimation of Health State Utility Values in Fabry Disease Using Vignette Development and Valuation.

ABSTRACT: Background: Health state utilities are measures of health-related quality of life that reflect the value placed on improvements in patients' health status and are necessary for estimation of quality-adjusted life-years. Health state utility data on Fabry disease (FD) are limited. In this study we used vignette (scenario) construction and valuation to develop health state utilities. Objectives: The aim of this study was to use vignette construction and valuation to estimate health state utility values suitable for inclusion in economic models of FD treatments. Methods: Health state vignettes were developed from semistructured qualitative telephone interviews with patients with FD and informed by published literature and input from an expert. Each vignette was valued in

SUBMITTER: Hughes D 

PROVIDER: S-EPMC10095067 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature