Nisin S, a Novel Nisin Variant Produced by Ligilactobacillus salivarius P1CEA3.

ABSTRACT: Recently, the food industry and the animal farming field have been working on different strategies to reduce the use of antibiotics in animal production. The use of probiotic producers of antimicrobial peptides (bacteriocins) is considered to be a potential solution to control bacterial infections and to reduce the use of antibiotics in animal production. In this study, Ligilactobacillus salivarius P1CEA3, isolated from the gastrointestinal tract (GIT) of pigs, was selected for its antagonistic activity against Gram-positive pathogens of relevance in swine production. Whole genome sequencing (WGS) of L. salivarius P1ACE3 revealed the existence of two gene clusters involved in bacteriocin production, one with genes encoding the class II bacteriocins salivaricin B (SalB) and Ab

SUBMITTER: Sevillano E 

PROVIDER: S-EPMC10095417 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature