Cognitive Stress Regulation in Schizophrenia Patients and Healthy Individuals: Brain and Behavior.

ABSTRACT: Stress is an important factor in the development, triggering, and maintenance of psychotic symptoms. Still, little is known about the neural correlates of cognitively regulating stressful events in schizophrenia. The current study aimed at investigating the cognitive down-regulation of negative, stressful reactions during a neuroimaging psychosocial stress paradigm (non-regulated stress versus cognitively regulated stress). In a randomized, repeated-measures within-subject design, we assessed subjective reactions and neural activation in schizophrenia patients (SZP) and matched healthy controls in a neuroimaging psychosocial stress paradigm. In general, SZP exhibited an increased anticipation of stress compared to controls (p = 0.020). During non-regulated stress, SZP showed increas

SUBMITTER: Kogler L 

PROVIDER: S-EPMC10095473 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature