Thermodynamic Parameters of Berberine with Kolliphor Mixtures Adsorption and Micellization.

ABSTRACT: The poor solubility of berberine (Ber) in water limits its practical use. Its solubility can be increased, among other ways, by the addition of surfactants. Of the surfactants, Kolliphor^® ELP (ELP) and Kolliphor^® RH 40 (RH40) can be very useful in this respect. The increase of Ber's solubility in water in the presence of ELP and RH40 should be reflected in the composition of the surface layers at the water-air interface and the micelles. The determined composition is reflected in the Gibbs energy of interactions of berberine with ELP and RH40 through the water phase and the standard Gibbs free energy, enthalpy, and entropy of adsorption and micellization. These energies were determined from the equations proposed by us, based on the Gibbs surface excess concentration

SUBMITTER: Szaniawska M 

PROVIDER: S-EPMC10095903 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature