Thraustochytrid hosts for expression of proteins relevant to SARS-CoV-2 intervention.

ABSTRACT: The emergence of COVID-19 as a global pandemic had sharply illustrated the limitations of research and development pipelines and scaled manufacturing. Although existing vaccines were created in record time, global deployment remains limited by regional production scales. Similarly, the most effective treatments for infected COVID-19 patients are also constrained by production scales as well as by the cost of production and thus expense per treatment. The need to produce these interventions more cost-effectively, at larger scales, in less time while retaining high quality is paramount. The ConamaxTM platform is based on a Thraustochytrid-an order of microorganisms well established in industry for world-scale production of omega-3 fatty acids by fermentation. Thraustochytrids, and the specie

SUBMITTER: Dahmen J 

PROVIDER: S-EPMC10096515 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature