Carnosine and Beta-Alanine Supplementation in Human Medicine: Narrative Review and Critical Assessment.

ABSTRACT: The dipeptide carnosine is a physiologically important molecule in the human body, commonly found in skeletal muscle and brain tissue. Beta-alanine is a limiting precursor of carnosine and is among the most used sports supplements for improving athletic performance. However, carnosine, its metabolite N-acetylcarnosine, and the synthetic derivative zinc-L-carnosine have recently been gaining popularity as supplements in human medicine. These molecules have a wide range of effects-principally with anti-inflammatory, antioxidant, antiglycation, anticarbonylation, calcium-regulatory, immunomodulatory and chelating properties. This review discusses results from recent studies focusing on the impact of this supplementation in several areas of human medicine. We queried PubMed, Web of Scie

SUBMITTER: Cesak O 

PROVIDER: S-EPMC10096773 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature