Response of peer relations and social activities to treatment with viloxazine extended-release capsules (Qelbree^® ): A post hoc analysis of four randomized clinical trials of children and adolescents with attention-deficit/hyperactivity disorder.

ABSTRACT:

Introduction

Attention-deficit/hyperactivity disorder (ADHD) is associated with impairments related to peer relations (PR) and social activities (SA). The objective of this post hoc analysis was to assess the degree to which viloxazine extended-release (viloxazine ER; viloxazine extended-release capsules; Qelbree^® ) improves clinical assessments of PR and SA in children and adolescents with ADHD.

Methods

Data were used from four Phase III placebo-controlled trials of 100 to 600 mg/day of viloxazine ER (N = 1354; 6-17 years of age). PR and SA were measured with the Peer Relations content scale of the Conners 3rd Edition Parent Short Form's Peer Relation content scale (C3PS-PR) and the Social Activities domain of the Weiss Functional Impairment Rating Scale-Parent R

SUBMITTER: Faraone SV 

PROVIDER: S-EPMC10097136 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature