Exploring the Potential Hormonal Effects of Tire Polymers (TPs) on Different Species Based on a Theoretical Computational Approach.

ABSTRACT: Tire polymers (TPs) are the most prevalent type of microplastics and are of great concern due to their potential environmental risks. This study aims to determine the toxicity of TPs with the help of molecular-dynamics simulations of their interactions with receptors and to highlight the differences in the toxicity characteristics of TPs in different environmental media (marine environment, freshwater environment, soil environment). For this purpose, five TPs-natural rubber, styrene-butadiene rubber (SBR), butadiene rubber, nitrile-butadiene rubber, and isobutylene-isoprene rubber-were analyzed. Molecular-dynamics calculations were conducted on their binding energies to neurotoxic, developmental, and reproductive receptors of various organisms to characterize the toxic effects of the five

SUBMITTER: Wang Y 

PROVIDER: S-EPMC10097371 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature