Assessing disease activity in pediatric Crohn's disease using ultrasound: the Pediatric Crohn's Disease Intestinal Ultrasound score.

ABSTRACT:

Objectives

Currently, there is no consensus on how to score Crohn's disease (CD) activity assessed by intestinal-ultrasound (IUS) in children. This study aimed to design an easy-to-use IUS score for disease activity in pediatric CD.

Methods

Children undergoing ileo-colonoscopy for CD assessment underwent IUS the day before ileo-colonoscopy, assessed with simple endoscopic score for CD (SES-CD). IUS features were compared to the SES-CD on segmental level. Multiple regression analyses, separately for terminal ileum (TI) and colon, were done to assess predictors of disease activity and to develop a model.

Results

In 74 CD patients (median 15 years, 48% female), 67 TI and 364 colon segments were assessed. Based on ROC-curves, bowel wall thickness (BWT) was categorized int

SUBMITTER: van Wassenaer EA 

PROVIDER: S-EPMC10097488 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature