Analysis of SARS-CoV-2 variants from patient specimens in Nevada from October 2020 to August 2021.

ABSTRACT: In early 2020, the emergence and spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the human population quickly developed into a global pandemic. SARS-CoV-2 is the etiological agent of coronavirus disease 2019 (COVID-19) which has a broad range of respiratory illnesses. As the virus circulates, it acquires nucleotide changes. These mutations are potentially due to the inherent differences in the selection pressures within the human population compared to the original zoonotic reservoir of SARS-CoV-2 and formerly naïve humans. The acquired mutations will most likely be neutral, but some may have implications for viral transmission, disease severity, and resistance to therapies or vaccines. This is a follow-up study from our early report (Hartley et al. J Genet Genomi

SUBMITTER: Payen SH 

PROVIDER: S-EPMC10098042 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature