Cytokine concentration in peripheral blood of patients with colorectal cancer.

ABSTRACT:

Introduction

The role of tumour secretory cytokines and peripheral circulatory cytokines in tumour progression has received increasing attention; however, the role of tumour-related inflammatory cytokines in colorectal cancer (CRC) remains unclear. In this study, the concentrations of various cytokines in the peripheral blood of healthy controls and patients with CRC at different stages were compared.

Methods

Peripheral blood samples from 4 healthy participants and 22 colorectal cancer patients were examined. Luminex beads were used to evaluate concentration levels of 40 inflammatory cytokines in peripheral blood samples.

Results

In peripheral blood, compared with healthy controls and early stage (I + II) CRC patients, advanced CRC (III + IV) patients had increased co

SUBMITTER: Li W 

PROVIDER: S-EPMC10098211 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature