Functional and anatomical alterations in bilateral vestibulopathy: A multimodal neuroimaging study and clinical correlation.

ABSTRACT:

Object

To study multimodal neuroimaging study including resting state functional MRI (rs-fMRI), anatomical connectivity and brain morphology in patients with bilateral vestibulopathy (BVP) and relationship with clinical correlation.

Methods

Thirteen patients with BVP (7 women; mean age ± SD = 63.5 ± 14.7 years, 22-80 years) and eighteen age and gender-matched controls were compared rs-fMRI and anatomical MRI. Also, we analyzed the relationship between multimodal neuroimaging and Dizziness Handicap Inventory score (DHI), Vestibular Disorders Activities of Daily Living Scale (VDRL), Geriatric Depression Scale (GDS) and Hospital Anxiety and Depression Scale (HADS).

Results

Compared with controls, BVP patients showed decreased functional connectivity among the key nodes o

SUBMITTER: Lee ES 

PROVIDER: S-EPMC10098449 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature