Risk factors for recurrent respiratory tract infections and acute respiratory failure in children with spinal muscular atrophy.

ABSTRACT:

Introduction

Assessment of and intervention for sleep-disordered breathing and malnutrition are related to the prevention of recurrent respiratory tract infections (RRTIs) and acute respiratory failure (ARF) in children with spinal muscular atrophy (SMA). However, specific standards for sleep-disordered breathing and malnutrition in the prevention of RRTIs and ARF have not been clarified.

Purpose

The study aimed to identify the risk factors and predictive indices for RRTIs and/or ARF in children with SMA.

Methods

In this retrospective study, the differences in clinical characteristics between patients with and without RRTIs and ARF were compared, and binary logistic regression analysis was carried out. The optimal cutoff points for positive predictors were obtained.

SUBMITTER: Guo W 

PROVIDER: S-EPMC10098738 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature