Novel strategies for cancer immunotherapy: counter-immunoediting therapy.

ABSTRACT: The advent of immunotherapy has made an indelible mark on the field of cancer therapy, especially the application of immune checkpoint inhibitors in clinical practice. Although immunotherapy has proven its efficacy and safety in some tumors, many patients still have innate or acquired resistance to immunotherapy. The emergence of this phenomenon is closely related to the highly heterogeneous immune microenvironment formed by tumor cells after undergoing cancer immunoediting. The process of cancer immunoediting refers to the cooperative interaction between tumor cells and the immune system that involves three phases: elimination, equilibrium, and escape. During these phases, conflicting interactions between the immune system and tumor cells result in the formation of a complex immune microe

SUBMITTER: Liu S 

PROVIDER: S-EPMC10099030 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature