Duration and characteristics of persistent headache following aneurysmal subarachnoid hemorrhage.

ABSTRACT:

Objective

To assess the long-term frequency, prognosis, and phenotype of persistent headache following aneurysmal subarachnoid hemorrhage (aSAH).

Background

Very little is known about long-term headache following aSAH with no studies looking beyond 3 years.

Methods

Retrospective analysis comparing aSAH cases to matched controls in the UK Biobank, a prospective cohort study. Headache frequency and phenotype were compared using group comparison tests. The relationship between headache frequency and time was assessed using correlation analysis.

Results

Headache was more frequent following aSAH (aSAH: 258/864 [29.9%] vs. controls: 666/3456 [19.3%], χ²  = 45.5, p < 0.001) at a median follow-up of 7.5 years. Headache frequency decreased over time (R_S<

SUBMITTER: Gaastra B 

PROVIDER: S-EPMC10099612 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature