In vivo T₁ mapping of neonatal brain tissue at 64 mT.

ABSTRACT:

Purpose

Ultralow-field (ULF) point-of-care MRI systems allow image acquisition without interrupting medical provision, with neonatal clinical care being an important potential application. The ability to measure neonatal brain tissue T₁ is a key enabling technology for subsequent structural image contrast optimization, as well as being a potential biomarker for brain development. Here we describe an optimized strategy for neonatal T₁ mapping at ULF.

Methods

Examinations were performed on a 64-mT portable MRI system. A phantom validation experiment was performed, and a total of 33 in vivo exams were acquired from 28 neonates with postmenstrual age ranging from 31⁺⁴ to 49⁺⁰  weeks. Multiple inversion-recovery turbo spin-echo sequence

SUBMITTER: Padormo F 

PROVIDER: S-EPMC10099617 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature