Conversion of a Au^I Fluorido Complex into an N-Fluoroamido Derivative: N-F versus Au-N Reactivity.

ABSTRACT: The Au^I complex [Au{N(F)SO₂ Ph}(SPhos)] (SPhos=dicyclohexyl(2',6'-dimethoxy[1,1'-biphenyl]-2-yl)phosphane) (2) bearing a fluoroamido ligand has been synthesized by reaction of the fluorido complex [Au(F)(SPhos)] (1) with NFSI (NFSI=N-fluorobenzenesulfonimide). A reaction with CO resulted in an unprecedented insertion into the N-F bond at 2. With the carbene precursor N₂ CH(CO₂ Et) N-F bond cleavage gave the Au-F bond insertion product [Au{CHF(CO₂ C₂ H₅ )}(SPhos)] (7). The presence of CNtBu led to Au-N cleavage at 2 and concomitant amide formation to give the cationic complex [Au(CNtBu)(SPhos)][N(F)SO₂ Ph)] (5), which reacted further to give FtBu as well as the cyanido complex [Au(CN)(SPhos)] (6). These

SUBMITTER: Rachor SG 

PROVIDER: S-EPMC10099710 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature