Valorization of Adhatoda vasica leaves: Extraction, in vitro analyses and in silico approaches.

ABSTRACT: Adhatoda vasica (also called Vasaka) is a traditional medicinal herb used traditionally for the relief of cough, asthma, nasal congestion, bronchial inflammation, upper respiratory infections, bleeding disorders, skin diseases, leprosy, tuberculosis, diabetes, allergic conditions, rheumatism, tumor, and many more diseases. The present study aims to investigate the biological activities of vasicine, a potent alkaloid from A. vasica with different biological/ pharmacological assays and in silico techniques. Vasicine showed antimicrobial activity as evidenced fromthe colony-forming unit assay. It showed antioxidant activity in ABTS scavenging assay (IC₅₀ = 11.5 μg/ml), ferric reducing power assay (IC₅₀ = 15 μg/ml), DPPH radical scavenging assay (IC_50</

SUBMITTER: Rudrapal M 

PROVIDER: S-EPMC10099809 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature