Neuronal activity patterns in microcircuits of the cerebellar cortical C3 zone during reaching.

ABSTRACT: The cerebellum is the largest sensorimotor structure in the brain. A fundamental organizational feature of its cortex is its division into a series of rostrocaudally elongated zones. These are defined by their inputs from specific parts of the inferior olive and Purkinje cell output to specific cerebellar and vestibular nuclei. However, little is known about how patterns of neuronal activity in zones, and their microcircuit subdivisions, microzones, are related to behaviour in awake animals. In the present study, we investigated the organization of microzones within the C3 zone and their activity during a skilled forelimb reaching task in cats. Neurons in different microzones of the C3 zone, functionally determined by receptive field characteristics, differed in their patterns of activity

SUBMITTER: Cerminara NL 

PROVIDER: S-EPMC10099968 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature