Management of polycythemia vera: A survey of treatment patterns in Italy.

ABSTRACT:

Objectives

Polycythemia vera (PV) is an acquired clonal hematopoietic stem cell disorder characterized by the overproduction of red blood cells. It has long been underlined that there are differences in treatment patterns in routine practice. Therapeutic strategies have also expanded, and in recent years the JAK1/JAK2 inhibitor ruxolitinib has emerged as a second-line therapeutic option in patients who are intolerant to or resistant to hydroxyurea. Determining the impact of changes on practice patterns is of interest, especially for aspects that lack detailed guidance for management.

Methods

To gain insights into treatment patterns by clinicians treating patients with PV in Italy, we carried out a survey of 60 hematologists and transfusion specialists. The questions covered:

SUBMITTER: Palumbo GA 

PROVIDER: S-EPMC10100449 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature