Change in the Gut Microbiome and Immunity by Lacticaseibacillus rhamnosus Probio-M9.

ABSTRACT: With the exploding growth of the global market for probiotics and the rapid awakening of public awareness to manage health by probiotic intervention, there is still an active debate about whether the consumption of probiotics is beneficial for nonpatients, which is due to the lack of systematic analysis based on time series multiomics data sets. In this study, we recruited 100 adults from a college in China and performed a random case-control study by using a probiotic (Lacticaseibacillus rhamnosus Probio-M9) as an intervention for 6 weeks, aiming to achieve a comprehensive evaluation and understanding of the beneficial effect of Probio-M9 consumption. By testing advanced blood immunity indicators, sequencing the gut microbiome, and profiling the gut metabolome at baseline and the end of t

SUBMITTER: Zhang M 

PROVIDER: S-EPMC10100958 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature