Secondary Metabolite Production Potential in a Microbiome of the Freshwater Sponge Spongilla lacustris.

ABSTRACT: Marine and freshwater sponges harbor diverse communities of bacteria with vast potential to produce secondary metabolites that may play an important role in protecting the host from predators and infections. In this work, we initially used cultivation and metagenomics to investigate the microbial community of the freshwater sponge Spongilla lacustris collected in an Austrian lake. Representatives of 41 bacterial genera were isolated from the sponge sample and classified according to their 16S rRNA gene sequences. The genomes of 33 representative isolates and the 20 recovered metagenome-assembled genomes (MAGs) contained in total 306 secondary metabolite biosynthesis gene clusters (BGCs). Comparative 16S rRNA gene and genome analyses showed very little taxon overlap between the recovered is

SUBMITTER: Graffius S 

PROVIDER: S-EPMC10100984 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature