Metatranscriptomic Sequencing Reveals Host Species as an Important Factor Shaping the Mosquito Virome.

ABSTRACT: Mosquitoes are important vector hosts for numerous viral pathogens and harbor a large number of mosquito-specific viruses as well as human-infecting viruses. Previous studies have mainly focused on the discovery of mosquito viruses, and our understanding of major ecological factors associated with virome structure in mosquitoes remains limited. We utilized metatranscriptomic sequencing to characterize the viromes of five mosquito species sampled across eight locations in Yunnan Province, China. This revealed the presence of 52 viral species, of which 19 were novel, belonging to 15 viral families/clades. Of particular note was Culex hepacivirus 1, clustering within the avian clade of hepaciviruses. Notably, both the viromic diversity and abundance of Aedes genus mosquitoes were signi

SUBMITTER: Li C 

PROVIDER: S-EPMC10101097 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature