A study on the association of placental and maternal urinary phthalate metabolites.

ABSTRACT:

Background

Phthalate exposure in pregnancy is typically estimated using maternal urinary phthalate metabolite levels. Our aim was to evaluate the association of urinary and placental tissue phthalates, and to explore the role of maternal and pregnancy characteristics that may bias estimates.

Methods

Fifty pregnancies were selected from the CANDLE Study, recruited from 2006 to 2011 in Tennessee. Linear models were used to estimate associations of urinary phthalates (2^nd, 3^rd trimesters) and placental tissue phthalates (birth). Potential confounders and modifiers were evaluated in categories: temporality (time between urine and placenta sample), fetal sex, demographics, social advantage, reproductive history, medication use, nutrition and adiposity. Molar

SUBMITTER: Liang HW 

PROVIDER: S-EPMC10101560 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature