Gender bias in fetal malformations: A cross-sectional study in Asian populations.

ABSTRACT:

Objectives

The aim of this study was to detect any gender bias in fetal malformation cases.

Design

This study was a cross-sectional, quantitative survey.

Subjects

Overall, 1,661 Asian fetal malformation cases involving induced abortions in the obstetrics department of the first Affiliated Hospital of Zhengzhou University from 2012 to 2021 were included.

Main outcome measures

Measurements of ultrasound detectable structural malformations were classified into 13 subtypes. Karyotyping, single nucleotide polymorphism (SNP) array, or sequencing diagnosis of these fetus was also included in the outcome measures.

Results

The sex ratio (male/female) of all malformation types was 1.446. Cardiopulmonary had the highest proportion of all malformation types with 28%

SUBMITTER: Zhang M 

PROVIDER: S-EPMC10101566 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature