Longer leukocyte telomere length increases cardiovascular mortality in type 2 diabetes patients.

ABSTRACT:

Aims

Leukocyte telomere length (LTL), as a biomarker of biological aging, is associated with the prevalence and complications of diabetes. This study aims to investigate the associations between LTL and all-cause and cause-specific mortality in patients with type 2 diabetes.

Methods

All participants with baseline LTL records were included from the National Health and Nutrition Examination Survey 1999-2002. Death status and its causes were ascertained for National Death Index based on International Classification of Diseases, Tenth Revision code. Cox proportional hazards regression models were established to estimate the hazard ratios (HRs) of LTL associating with all-cause and cause-specific mortality.

Results

The study enrolled 804 diabetic patients with the mean fol

SUBMITTER: Chen Z 

PROVIDER: S-EPMC10101828 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature