Prenatal bisphenol A and S exposure and atopic disease phenotypes at age 6.

ABSTRACT:

Background

Atopic disease may be influenced by prenatal and early life exposure to endocrine disrupting chemicals, including bisphenols, but results from epidemiological studies have been mixed. This study aimed to extend the epidemiological literature, hypothesizing that children with higher prenatal bisphenol exposure are more likely to have childhood atopic disease.

Methods

Urinary bisphenol A (BPA) and S (BPS) concentrations were measured in each trimester from 501 pregnant women in a multi-center, prospective pregnancy cohort. Ever asthma, current asthma, wheeze, and food allergy) were assessed at age six via standardized ISAAC questionnaire. We constructed generalized estimating equations to examine BPA and BPS exposure jointly at each trimester for each atopy phenotyp

SUBMITTER: Gaylord A 

PROVIDER: S-EPMC10101912 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature