Macular atrophy at 5 years after photodynamic therapy for polypoidal choroidal vasculopathy.

ABSTRACT:

Purpose

To investigate predictors for macular atrophy (MA) involving the fovea after photodynamic therapy (PDT) followed by pro re nata (PRN) treatment for polypoidal choroidal vasculopathy (PCV).

Methods

This prospective observational study analysed treatment-naïve eyes with symptomatic PCV without MA at baseline which were followed up for 5 years. All eyes were initially treated with PDT, followed by a PRN regimen of anti-vascular endothelial growth factor (VEGF) therapy and/or PDT. We assigned eyes with and eyes without development of MA involving the fovea 5 years after the initial treatment into MA and non-MA groups, respectively. Baseline parameters and the number of treatments were compared between the two groups.

Results

Seventy-two eyes of 69 consecutive pati

SUBMITTER: Kawai K 

PROVIDER: S-EPMC10102034 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature