Exploration of the prognostic value of the resection of adult brainstem high-grade glioma based on competing risk model, propensity score matching, and conditional survival rate.

ABSTRACT:

Background

Adult brainstem high-grade glioma (HGG) is a refractory disease, and the treatment strategy of resection is still controversial.

Objective

To investigate the prognostic value of brainstem HGG resection in adults.

Methods

We collected 126,386 samples from the Surveillance, Epidemiology, and End Results (SEER) database between 1998 and 2016, and screened 973 patients diagnosed with adult brainstem HGG, who were in turn, grouped into 899 cases of non-resections and 74 cases of resections. Competing risk models were used to screen independent prognostic factors. Propensity score matching (PSM) was performed to reduce the influence of confounding factors. Conditional survival (CS) rate was considered to evaluate the changes in overall survival (OS) and disease-s

SUBMITTER: Zhang D 

PROVIDER: S-EPMC10102064 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature