Atrophy in subcortical gray matter in adult patients with moyamoya disease.

ABSTRACT:

Background

Acute cerebrovascular accidents, long-term hypoperfusion, and/or remote neuronal degeneration may lead to structural alterations in patients with moyamoya disease (MMD). This study sought to comprehensively investigate the distribution characteristics of subcortical gray matter volume and their correlations with angiographic changes in the intracranial artery in patients with MMD.

Method

One hundred forty-two patients with MMD and 142 age- and sex-matched healthy controls underwent 3-dimensional high-resolution structural magnetic resonance imaging. Volumes of subcortical gray matter and subregions of the hippocampus and amygdala were calculated, and the degree of stenosis/occlusion of intracranial arteries in patients with MMD was evaluated on MR angiography.

SUBMITTER: Zuo Z 

PROVIDER: S-EPMC10102099 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature