Association between temporal patterns of baroreflex sensitivity after traumatic brain injury and prognosis: a preliminary study.

ABSTRACT:

Introduction

Traumatic brain injury (TBI) may lead to an increase in intracranial pressure (ICP) as well as impairment of cerebral vascular reactivity and the autonomic nervous system. This study aimed to investigate individual patterns of changes in baroreflex sensitivity (BRS) along with the assessment of pressure reactivity index (PRx) and ICP after TBI.

Materials and methods

Twenty-nine TBI patients with continuous arterial blood pressure (ABP) and ICP monitoring were included. BRS was calculated using the sequential cross-correlation method. PRx was estimated using slow-wave oscillations of ABP and ICP. Outcome was assessed using the Glasgow Outcome Scale.

Results

Pooled data analysis of the lower breakpoint during the week that followed TBI revealed that BRS rea

SUBMITTER: Uryga A 

PROVIDER: S-EPMC10102132 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature