Alterations in gut microbiota and urine metabolomics in infants with yin-deficiency constitution aged 0-2 years.

ABSTRACT:

Background

Based on the constitution theroy, infants are classified into balanced constitution (BC) and unbalanced constitution. Yin-deficiency constitution (YINDC) is a common type of unbalanced constitutions in Chinese infants. An infant's gut microbiota directly affects the child's health and has long-term effects on the maturation of the immune and endocrine systems throughout life. However, the gut microbiota of infants with YINDC remains unknown. Herein, we aimed to evaluate the intestinal flora profiles and urinary metabolites in infant with YINDC, find biomarkers to identify YINDC, and promote our understanding of infant constitution classification.

Methods

Constitutional Medicine Questionnaires were used to assess the infants' constitution types. 47 infants with 21

SUBMITTER: Zhao H 

PROVIDER: S-EPMC10102239 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature