Helicobacter pylori infection increases the risk of thyroid nodules in adults of Northwest China.

ABSTRACT:

Background

Thyroid nodules (TNs) are very common in the adults of Northwest China. The role of Helicobacter pylori (H. pylori) infection in TNs is poorly investigated and even with controversial conclusions. Our study aimed at highlighting the relationship between H. pylori infection and the risk of TNs.

Methods

9,042 individuals were enrolled with thyroid ultrasonography and ¹⁴C-urea breath test (¹⁴C-UBT). Baseline characteristics and relevant covariates were obtained, including basic and laboratory indicators. After applying the exclusion criteria, 8,839 patients were included and divided into 2 groups: a cross-sectional study of single follow-up (n=8,711) and a retrospective cohort study of multiple follow-ups for 5 years

SUBMITTER: Di J 

PROVIDER: S-EPMC10102366 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature