Higher serum selenium concentration is associated with lower risk of all-cause and cardiovascular mortality among individuals with chronic kidney disease: A population-based cohort study of NHANES.

ABSTRACT:

Background

Selenium is an essential nutrient and trace element required for human health and plays an important role in antioxidative and anti-inflammatory processes. However, the long-term impact of selenium levels on the health of patients with chronic kidney disease remains unclear.

Method

Participants in this study were 3,063 CKD adults from the Third National Health and Nutrition Examination Survey (NHANES 1999-2000, 2003-2004, and 2011-2018). The mortality status and the cause of death of the study participants were obtained from the National Death Index records. For all-cause and cardiovascular disease (CVD) mortality, the models employed to estimate hazard ratios (HRs) and 95% CI were Cox proportional hazard models and competing risk models, respectively.

Result</

SUBMITTER: Zhu D 

PROVIDER: S-EPMC10102510 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature