Intra and inter-individual variability in functional connectomes of patients with First Episode of Psychosis.

ABSTRACT: Patients with Schizophrenia may show different clinical presentations, not only regarding inter-individual comparisons but also in one specific subject over time. In fMRI studies, functional connectomes have been shown to carry valuable individual level information, which can be associated with cognitive and behavioral variables. Moreover, functional connectomes have been used to identify subjects within a group, as if they were fingerprints. For the particular case of Schizophrenia, it has been shown that there is reduced connectome stability as well as higher inter-individual variability. Here, we studied inter and intra-individual heterogeneity by exploring functional connectomes' variability and related it with clinical variables (PANSS Total scores and antipsychotic's doses). Our samp

SUBMITTER: Tepper A 

PROVIDER: S-EPMC10102560 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature