Ablative Margins of Colorectal Liver Metastases Using Deformable CT Image Registration and Autosegmentation.

ABSTRACT: Background Confirming ablation completeness with sufficient ablative margin is critical for local tumor control following colorectal liver metastasis (CLM) ablation. An image-based confirmation method considering patient- and ablation-related biomechanical deformation is an unmet need. Purpose To evaluate a biomechanical deformable image registration (DIR) method for three-dimensional (3D) minimal ablative margin (MAM) quantification and the association with local disease progression following CT-guided CLM ablation. Materials and Methods This single-institution retrospective study included patients with CLM treated with CT-guided microwave or radiofrequency ablation from October 2015 to March 2020. A biomechanical DIR method with AI-based autosegmentation of liver, tumors, and ablation zo

SUBMITTER: Lin YM 

PROVIDER: S-EPMC10102669 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature