Comparison of single-postlabeling delay and seven-delay three-dimensional pseudo-continuous arterial spin labeling in the assessment of intracranial atherosclerotic disease.

ABSTRACT:

Background

The assessment of cerebral blood flow (CBF) is crucial in the evaluation of intracranial atherosclerotic disease. This study was performed to compare single postlabeling delay (PLD) 3-dimensional pseudo-continuous arterial spin labeling (3D-pCASL) and 7-delay 3D-pCASL magnetic resonance imaging in patients with intracranial atherosclerotic stenosis.

Methods

A total of 26 patients with moderate to severe atherosclerotic stenosis or occlusion of an intracranial artery were prospectively enrolled in the study. Perfusion parameters were obtained in various regions of interest (ROIs), namely CBF for single PLDs of 1,525 ms (CBF_{1525 ms}), 2,025 ms (CBF_{2025 ms}), and 2,525 ms (CBF_{2525 ms}) with 3D-pCASL, as well as arterial transit time (ATT

SUBMITTER: Yu H 

PROVIDER: S-EPMC10102769 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature