Sensory impairment and algorithmic classification of early cognitive impairment.

ABSTRACT:

Introduction

Sensory impairment (SI) is linked to cognitive decline, but its association with early cognitive impairment (ECI) is unclear.

Methods

Sensory functions (vision, hearing, vestibular function, proprioception, and olfaction) were measured between 2012 and 2018 in 414 Baltimore Longitudinal Study of Aging (BLSA) participants (age 74 ± 9 years; 55% women). ECI was defined as 1 standard deviation below age-, sex-, race-, and education-specific mean performance in Card Rotations or California Verbal Learning Test immediate recall. Log binomial models (cross-sectional analysis) and Cox regression models (time-to-event analysis) were used to examine the association between SI and ECI.

Results

Cross-sectionally, participants with ≥3 SI had twice the prevalence of E

SUBMITTER: Cai Y 

PROVIDER: S-EPMC10103182 | biostudies-literature | 2023 Apr-Jun

REPOSITORIES: biostudies-literature